Randomized study of vinorelbine (VRB) versus vindesine (VDS) in previously untreated stage IIIB or IV non-small-cell lung cancer (NSCLC)
نویسندگان
چکیده
منابع مشابه
A multicenter phase II trial of vinorelbine plus gemcitabine in previously untreated inoperable (Stage IIIB/IV) non-small cell lung cancer.
STUDY OBJECTIVE Vinorelbine and gemcitabine are two active single agents used in the treatment of non-small cell lung cancer (NSCLC). A clinical trial was conducted to evaluate the efficacy and toxicity of vinorelbine plus gemcitabine in patients with inoperable (stage IIIB or IV) NSCLC. DESIGN A multicenter phase II study. Vinorelbine, 20 mg/m(2), was given as a 10-min IV infusion, followed ...
متن کاملExcision of the primary in stage IV non-small cell lung cancer (NSCLC): A feasibility study
Method A prospective lung cancer database was analysed to identify patients with stage IV lung cancer. Inclusion criteria included: WHO performance status of 0-2 and histologically confirmed NSCLC. Patients with cerebral metastases were excluded. The images of these patients were independently reviewed by two surgeons to determine the suitability for a VATS wedge resection of the primary lesion...
متن کاملTherapy for stage IIIB and stage IV non-small cell lung cancer.
The treatment options for unresectable stage III NSCLC include definitive RT, chemotherapy, combined chemoradiotherapy, or supportive care. Compared with radiation alone or chemotherapy alone, the combination of chemotherapy and standard RT confers a modest survival benefit at the cost of increased toxicity for patients with an excellent performance status. For metastatic disease, combination c...
متن کاملSurvival in untreated early stage non-small cell lung cancer.
BACKGROUND The aim of this study was to determine the survival of untreated stage I and II in non-small cell lung cancer (NSCLC) patients. PATIENTS AND METHODS A retrospective analysis of medical charts of all patients diagnosed with early stage NSCLC, between January 1990 and December 2001, was conducted and patients who were not treated were identified. Data on patient's age, gender, stage ...
متن کاملOral vinorelbine and cisplatin with concomitant radiotherapy in stage III non-small cell lung cancer (NSCLC): a feasibility study.
BACKGROUND Concurrent chemoradiotherapy has improved survival in inoperable stage III non-small cell lung cancer (NSCLC). This phase I trial was performed in order to establish a dose recommendation for oral vinorelbine in combination with cisplatin and simultaneous radiotherapy. PATIENTS AND METHODS Previously untreated patients with stage IIIB NSCLC received concurrent chemoradiotherapy wit...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1996
ISSN: 0923-7534
DOI: 10.1093/oxfordjournals.annonc.a010760